Primary Peritoneal Cancer Treatment

Primary peritoneal cancer is a rare form of cancer that affects the peritoneum, the thin tissue that lines the abdominal cavity and covers the organs within. It is similar to ovarian cancer and is often treated in the same way. This article will provide an overview of the different treatment options for primary peritoneal cancer.
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Chemotherapy

Chemotherapy is a common treatment for primary peritoneal cancer and is often the first line of treatment. It involves using drugs to kill cancer cells and prevent them from growing and dividing. Chemotherapy for primary peritoneal cancer is usually given intravenously (through a vein) or directly into the abdominal cavity through a tube. This is known as intraperitoneal chemotherapy. The drugs used for chemotherapy can vary, but some commonly used ones for primary peritoneal cancer include cisplatin, paclitaxel, and carboplatin. Chemotherapy is usually given in cycles, with a period of treatment followed by a rest period. The length of treatment and the number of cycles will depend on the individual case and the stage of the cancer. Chemotherapy can cause side effects such as nausea, vomiting, hair loss, and fatigue, but these can be managed with medication and usually subside once treatment is completed.

Surgery

Surgery is another common form of treatment for primary peritoneal cancer. It involves removing the cancerous tissue and, in some cases, nearby lymph nodes. The type of surgery will depend on the stage and location of the cancer. In some cases, a hysterectomy (removal of the uterus) and oophorectomy (removal of the ovaries) may also be necessary. Surgery is often combined with other treatments, such as chemotherapy, to increase its effectiveness. Recovery time and potential side effects will vary depending on the extent of the surgery and the individual’s overall health.

Radiation Therapy

Radiation therapy uses high-energy beams to kill cancer cells. It is not commonly used to treat primary peritoneal cancer, but may be recommended for certain cases. It is usually delivered externally, targeting the affected area from outside the body. This is known as external beam radiation therapy. In some cases, radiation may be delivered internally, placing radioactive material near the cancer cells. This is known as brachytherapy. Radiation therapy can cause side effects such as nausea, fatigue, and changes in skin appearance. These side effects are usually temporary and can be managed with medication.

Targeted Therapy

Targeted therapy is a newer form of cancer treatment that specifically targets cancer cells without harming healthy cells. This type of treatment may be used for primary peritoneal cancer that has not responded to other treatments or has returned after treatment. It works by targeting specific proteins or genes that help cancer cells grow and survive. Targeted therapy can be given in pill form or through an IV infusion. Some commonly used targeted therapy drugs for primary peritoneal cancer include bevacizumab, olaparib, and rucaparib. Side effects may vary depending on the specific drug used, but may include nausea, fatigue, and changes in blood pressure.

Clinical Trials

Clinical trials are research studies that test new treatments or combinations of treatments in humans. They are an important part of developing new and improved treatments for primary peritoneal cancer. Participation in a clinical trial is voluntary and can provide access to promising new treatments that are not yet available to the general public. If you are interested in participating in a clinical trial, speak to your doctor about potential options and whether you are eligible to participate.

Summary

  • Primary peritoneal cancer is a rare form of cancer that affects the peritoneum.
  • Treatment options for primary peritoneal cancer include chemotherapy, surgery, radiation therapy, targeted therapy, and clinical trials.
  • Chemotherapy is often the first line of treatment and involves using drugs to kill cancer cells.
  • Surgery may be necessary to remove the cancerous tissue.
  • Radiation therapy may be used in certain cases to kill cancer cells.
  • Targeted therapy specifically targets cancer cells without harming healthy cells.
  • Clinical trials are research studies that test new treatments and are an important part of developing new and improved treatments for primary peritoneal cancer.